Blar i forfatter "Nordrehaug, Jan Erik"

Viser treff 1-6 av 6

    • Analyses of Increased Mortality in New and Known Diabetes in Patients with Coronary Disease Enrolled in the NORSTENT Randomized Study 

      Mølstad, Per; Nordrehaug, Jan Erik; Steigen, Terje; Wilsgaard, Tom; Wiseth, Rune; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05)
      Background: NORSTENT trial randomized 9,013 patients to percutaneous coronary intervention with drug-eluting stents (DES) or bare-metal stents (BMS) with a 5-year follow-up. Among the patients, 5,512 had measured either fasting glucose level or percent glycated hemoglobin (HbA1c) at the index procedure. That cohort constitutes the present study population analyzing mortality and evaluating treatment ...

    • Drug-Eluting versus Bare-Metal Stents in Saphenous Vein Grafts Compared to Native Coronary Vessels: The Norwegian Coronary Stent Trial Study 

      Mølstad, Per; Nordrehaug, Jan Erik; Steigen, Terje; Wilsgaard, Tom; Wiseth, Rune; Rotevatn, Svein; Mannsverk, Jan Torbjørn; Larsen, Tommy; Larsby, Kristina; Skarstad, Sigrun; Fosse, Eivind Øygard; Dahl-Eriksen, Øystein; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01)
      Background: Drug-eluting stents (DES) reduce target lesion revascularization (TLR) with no effect on mortality or myocardial infarction (MI) compared to bare-metal stents (BMS) in native vessels. Randomized stent studies in saphenous vein grafts (SVG) are few and the reported effects are ambiguous. The Norwegian Coronary Stent Trial study is the first to randomize lesions to percutaneous coronary ...

    • The effect of drug-eluting stents on target lesion revascularization in native coronary arteries: Results from the NORSTENT randomized study 

      Mølstad, Per; Nordrehaug, Jan Erik; Steigen, Terje; Melvær, Giil Lasse; Wilsgaard, Tom; Wiseth, Rune; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06)
      <i>Background</i>: The NORSTENT trial randomized 9,013 patients to percutaneous coronary intervention (PCI) with a drug-eluting stent (DES) or bare-metal stent (BMS) with 5-year follow-up. No difference was found in the composite primary outcome of death from any cause and nonfatal spontaneous myocardial infarction after a median of 5 years of follow-up. Secondary outcomes included repeat ...

    • The Effect of Protease-Activated Receptor-1 (PAR-1) Inhibition on Endothelial-Related Biomarkers in Patients with Coronary Artery Disease 

      Nilsen, Dennis W.T.; Røysland, Michelle; Ueland, Thor; Aukrust, Pål; Michelsen, Annika Elisabet; Staines, Harry; Barvik, Ståle; Kontny, Frederic; Nordrehaug, Jan Erik; Bonarjee, Vernon V S (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-20)
      Abstract Background: Vorapaxar has been shown to reduce cardiovascular mortality in postmyocardial infarction (MI) patients. Pharmacodynamic biomarker research related to protease-activated receptor-1 (PAR-1) inhibition with vorapaxar in humans has short follow-up (FU) duration and is mainly focused on platelets rather than endothelial cells. Aim: This article assesses systemic changes in ...

    • Incidence and risk factors for major bleeding among patients undergoing percutaneous coronary intervention: Findings from the Norwegian Coronary Stent Trial (NORSTENT) 

      Samuelsen, Per-Jostein; Eggen, Anne Elise; Steigen, Terje; Wilsgaard, Tom; Kristensen, Andreas; Skogsholm, Anne; Holme, Elizabeth; van den Heuvel, Christian; Nordrehaug, Jan Erik; Bendz, Bjørn; Nilsen, Dennis W.T.; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-04)
      Introduction - Bleeding is a concern after percutaneous coronary intervention (PCI) and subsequent dual antiplatelet therapy (DAPT). We herein report the incidence and risk factors for major bleeding in the Norwegian Coronary Stent Trial (NORSTENT). <p> <p>Materials and methods - NORSTENT was a randomized, double blind, pragmatic trial among patients with acute coronary syndrome or stable coronary ...

    • Plasma concentrations and dietary intakes of choline and betaine in association with atrial fibrillation risk: Results from 3 prospective cohorts with different health profiles 

      Zuo, Hui; Svingen, Gard Frodahl Tveitevåg; Tell, Grethe S.; Ueland, Per Magne; Vollset, Stein Emil; Pedersen, Eva Ringdal; Ulvik, Arve; Meyer, Klaus; Nordrehaug, Jan Erik; Nilsen, Dennis W.T.; Bønaa, Kaare; Nygård, Ottar (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-12)
      <p><i>Background - </i>Although choline metabolism has been associated with atherosclerotic heart disease, less research attention has been paid to the associations of choline and its oxidative metabolite betaine with cardiac arrhythmias. <p><i>Methods and Results - </i>We evaluated associations of plasma concentrations and dietary intakes of choline and betaine with long-term atrial fibrillation ...